A role for cellular senescence in birth timing
نویسندگان
چکیده
منابع مشابه
Endometrial cellular senescence contributes to preterm birth
Preterm birth is a major global health issue, and its causes and underlying mechanism remain obscure. We recently established a mouse model of spontaneous preterm birth. In this model, endometrial cellular senescence early in pregnancy via mTORC1-p21 signaling is a major contributor of preterm birth and fetal death, and these adverse phenotypes are restored by the inhibition of mTORC1 or p21. T...
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ژورنال
عنوان ژورنال: Cell Cycle
سال: 2017
ISSN: 1538-4101,1551-4005
DOI: 10.1080/15384101.2017.1371888